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Posts Tagged ‘dentistry at University of Sydney’

Friday, July 28th, 2017

Sydney Faculty of Dentistry lab’s 3D printing may revolutionise root canal therapy

Researchers have created 3D-printed artificial blood vessels that could revolutionize root canal therapy to help people retain fully functioning teeth.

Sydney Dental School

Learn more about Sydney Dental School

Professor Luiz Bardessono and his team published the breakthrough in Scientific Reports. He leads The Bertassoni Lab at Oregon Health and Science University and the Bioengineering Laboratory in the University of Sydney Faculty of Dentistry.

While current root canal therapy is effective in saving an infected or decayed tooth, the procedure may cause teeth to become brittle and susceptible to fracture over time.

Based on previous work fabricating artificial capillaries, the researchers placed a fibre mould made of sugar molecules across the root canal of extracted human teeth and injected a material similar to proteins found in the body filled with dental pulp cells.

The researchers removed the fiber to make a long microchannel in the root canal and inserted endothelial cells (cellls that are involved in filtering gases, fluid and molecules across cell membranes) isolated from the interior lining of blood vessels.

They then removed the fibre to make a long microchannel in the root canal and inserted endothelial cells isolated from the interior lining of blood vessels. After seven days, dentin-producing cells appeared near the tooth walls and artificial blood vessels formed inside the tooth.

Professor Bertassoni said the research proved artificial blood vessels can be used to treat root canals.

“This result proves that fabrication of artificial blood vessels can be a highly effective strategy for fully regenerating the function of the teeth.

“We believe that this finding may change the way that root canal treatments are done in the future,” said Professor Bertassoni.

Current root canal treatment involves removing infected dental tissues and replacing them with synthetic biomaterials covered by a protective crown, which often results in further decay over time.

“This process eliminates the tooth’s blood and nerve supply, rendering it lifeless and void of any biological response or defence mechanism.

“Without this functionality, adult teeth may be lost much sooner, which can result in much greater concerns, such as the need for dentures or dental implants,” he said.

Research at the Sydney Faculty of Dentistry

Sydney Dentistry’s multidisciplinary research approach brings together the complementary expertise of the university’s faculties, centres and institutes with that of their affiliated teaching hospitals, institutes and international research partnerships. Sydney dentistry researchers are not limited by the confines of the mouth, but enhance studies in fundamental cell biology, microbiology, molecular biology and biomechanics with their dental expertise—it is their goal to “put the mouth into health!”

Research areas

Dentistry research at the University of Sydney is structured around a number of cross-disciplinary themes that are focused on improving health outcomes. These themes encompass microbial pathogenicity, biomaterials, implant technology, cell biology, pathology, minimal intervention therapies for management of caries, education, and public health.

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Do you think studying at the University of Sydney Faculty of Dentistry is right for you? Please contact OzTREKK’s Australian Dental Schools Admissions Officer Caitlin Sargeant at caitlin@oztrekk.com for more information!

Wednesday, July 5th, 2017

Dentistry research at the front line of tobacco intervention

Dentistry research is at the front line of tobacco intervention

Sydney Dental School

Learn more about Sydney Dental School

Smoking is a primary risk factor for periodontal disease and oral cancer and is one of the leading preventable causes of death. Healthcare providers have access to evidence-based guidelines that can help patients quit smoking; however, the translation of that knowledge and adoption into daily practice remains low. Healthcare providers are missing opportunities to address tobacco-use with their patients due to limited time and lack of health behaviour change expertise.

Concerns around how best to manage patients’ tobacco-use are raised in dental settings across the world. Innovative strategies are emerging in the behavioural sciences area; however, screening, brief intervention, and referral to treatment (SBIRTs) methods can be difficult to apply to the individual patients.

How is dentistry research at the University of Sydney addressing this issue?

Professor Heiko Spallek, Pro-Dean of Dentistry at the University of Sydney  and Dr Brad Rindal, Associate Dental Director for Research at HealthPartners Institute, Minnesota are conducting a clinical trial to evaluate the effectiveness of Clinical Decision Support (CDS) to improve dental provider delivery of SBIRTs.

What does the clinical trial involve?

The overarching goal of this research is to reduce smoking-associated morbidity and mortality by increasing the number of dental patients who are referred for tobacco cessation counseling. This program aims to

  • evaluate the effectiveness of clinical decision support (CDS) and,
  • improve dental provider delivery of brief tobacco interventions and referrals to tobacco quitlines for further tobacco counseling.

In this research, the CDS is being integrated within two commonly used electronic dental record systems and will generate personalised evidence-based recommendations for dental providers. These records will help dental professionals to actively engage with patients who smoke as part of the course of usual dental care.

The tobacco CDS will be tested within two dental schools, the School of Dental Medicine at the University of Pittsburgh and the Indiana University School of Dentistry as well as sixteen private-practice clinics. The research project is funded by the National Institute of Dental and Craniofacial Research for over two million US dollars.

Sydney Dentistry’s Doctor of Dental Medicine

The Sydney Dental School’s DMD is a graduate-entry program that has been purposefully designed to adhere to the well-rounded course structure of the North American postgraduate model, but has also maintained the sophisticated clinical training for which the University of Sydney has come to be renowned, giving students an applicable knowledge of dental health from the community to the laboratory.

Program: Doctor of Medicine (MD)
Location: Sydney, New South Wales (Camperdown/Darlington campus)
Semester intake: February each year
Duration: 4 years

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Are you interested in dentistry at the University of Sydney ? Email OzTREKK’s Australian Dental Schools Admissions Officer Adam Smith at adam@oztrekk.com for more information!